Clinical Trials

A new clinical research study is being conducted in your area to determine the effects of a potential new treatment, clobazam, in children and adults with LGS or those who experience LGS symptoms. Participation in a clinical study can help researchers learn more about the disease and can allow patients to gain access to medical care directly related to the study.

Atkins Diet Protocol

Adult IRB# 04-02-27-08
Pediatric IRB# 05-01-26-05
Primary investigator, Dr. Eric Kossoff, 410.614.6054

This trial is now in the research phase for teens and adults. The investigators use the Atkins diet to induce benign dietary ketosis and monitor the effect of the Atkins diet on seizure control. Children as young as 8 years of age can participate.

Inclusion Criteria:

  • 1 or more seizure(s) per week (any type)
  • 2 or more medications tried
  • Can't have kidney, heart or cholesterol disease
  • Can't have major psychiatric disorders
  • Can't have tried ketogenic diet in the past year
  • Willing to make 4 trips over a 6-month period
  • Labs, clinic visits and dietitian are free (for adult patients)
http://www.hopkinsneuro.org/epilepsy/clinical_trials.cfm